| December 7, 2015

b-catenin functions as a cytoskeletal protein and a transcription activator. It plays a crucial role in early sea urchin development by presumably activating genes. Currently, b-catenin is known to activate Pmar1. Assume none of b-catenin-target genes has been discovered. Propose to prepare three sets of sea urchin embryos in order to identify genes up-regulated as well as down-regulated by b-catenin. And justify your strategy.

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